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Chongqing Key natural product synthesis
Natural Product Synthesis, supplied by Chongqing Key, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/natural+product+synthesis/natural+product+synthesis/pm41467877-164-127-123
Average 86 stars, based on 1 article reviews
natural product synthesis - by Bioz Stars, 2026-10
86/100 stars

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Article Title: Visible Light‐Mediated [4+2] Annulation of Silylimines with Olefins to 1‐Aminotetralins Enabled by Diradical Hydrogen Atom Transfer of C−H Bonds
Article Snippet: In this sense, Hou and co-workers recently disclosed a diastereoselective [4+2] annulation of aldimines with alkenes employing half- [*] Q. Liu, Y. Huang, X. Zhou, Prof. Dr. Y. Xiong Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331 (P. R. China) E-mail: yxiong@cqu.edu.cn Prof. Dr.

Article Title: DNA‐Compatible Nitriles Hydrolysis for Late‐Stage Functionalization of DNA‐Encoded Libraries
Article Snippet: It is essential to [a] T. Zhang,+ X. Fang,+ X. Wang, H. Wang, G. Zhang, Y. Li, Y. Li Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China E-mail: yfli3@cqu.edu.cn yizhouli@cqu.edu.cn [b] X. Fang,+ W. Fang Pharmaceutical Department, Chongqing University Three Gorges Hospital, Chongqing University, Chongqing 404100, China E-mail: delight9924@cqu.edu.cn [c] G. Zhang, Y. Li, Y. Li Chemical Biology Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China [+] Tianyang Zhang and Xianfu Fang contributed equally to this work.

Article Title: Organocatalytic Asymmetric Dearomatizing Hetero-Diels-Alder Reaction of Nonactivated Arenes.
Article Snippet: Nonactivated arenes, such as benzene derivatives, are chemically inert due to their intrinsic aromaticity and low polarity.. The catalytic asymmetric dearomatization (CADA, coined by You and co-workers) of the nonactivated arenes represents a formidable challenge.. We herein demonstrated an organocatalytic asymmetric dearomatizing hetero-Diels−Alder reaction of benzene derivatives.

Article Title: Enantioselective Synthesis and Biological Evaluation of Pyrrolidines Bearing Quaternary Stereogenic Centers.
Article Snippet: Molecular complexity plays an increasingly important role in the modern pharmaceutical industry.. Setting up multiple stereogenic centers in privileged substructures may give rise to improved or even unprecedented bioactivities; however, this area remains largely unexplored due to the tremendous synthetic challenges.. Herein, we report a series of multisubstituted pyrrolidines with four continuous stereogenic centers, including up to two aza-QSCs (quaternary stereogenic centers).

Article Title: Stereoselective Dihalogenation of Alkynes to Access Enantioenriched Z -Vicinal Dihaloalkene Atropisomers.
Article Snippet: The stereoselective construction of Z-configured olefins remains a fundamental challenge in synthetic chemistry, particularly when additional stereogenic elements with high enantioselectivity are simultaneously introduced.. Furthermore, vicinal dihaloalkenes are privileged scaffolds in organic and medicinal chemistry, and the traditional protocol for preparing vicinal dihaloalkenes relies on a halonium intermediate−mediated pathway and typically yields E-configured adducts.. Herein, we report the catalytic stereoselective synthesis of enantioenriched Z-vicinal dihaloalkene atropisomers in high yields (up to 95%) with excellent enantioselectivity (up to 99%) and a Z/E ratio of more than 20:1.

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Article Title: Controllable Reductive Alkylation of Monodentate Phosphine Ligands under Iron Catalysis.
Article Snippet: Unsymmetrical aryldialkylphosphine ligands, characterized by their electron-rich and sterically hindered nature, play a pivotal role in the fine-tuning of transition-metal catalysts during catalytic processes.. However, their synthesis remains challenging via conventional approaches.. Herein, we report an iron-catalyzed reductive cross-coupling of aryldialkylphosphine ligands with alkyl bromides under mild conditions and successfully extend this strategy to diarylalkylphosphines.



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